Our Research
Our Research
This division is an integral part of the Department of
Cardiothoracic Surgery and is headed by Edith Hochhauser Ph.D. Students of
Master and Ph.D degrees play an active role and conduct their research at the
laboratory. The group publishes several original articles and reviews in the
leading scientific literature. Residents
of various medical departments conduct their mandatory basic research program
in this laboratory. Prevention and amelioration
of cardiac failure as a result of cardiomyopathy are the main focus of our
research. We have developed a special model of cardiomyopathy in an animal
model to study drug and genetic manipulations both invivo and invitro. The research topics are conducted with collaborations
of the leading cardiac researchers in Israel and abroad.
Research Topics:
1. Cardioprotective
caloric restriction signaling pathway in
attenuation of cardiovascular risk in diabetic
obese mice
2. The role
of Toll-Like Receptor 4 as mediators of cardiac dysfunction during sepsis and
myocardial ischemia
3. The role
of new and old antidiabetic therapies in attenuation of diabetic cardiomyopathy
4. Drug and
gene therapy for Cardiomyopathy in Danon disease
