Figure 1. Model for the impaired regeneration mechanism in dy2J/dy2J mouse skeletal muscle (Yanay et al 2019).
Figure 2. Treatment with nano-liposomes (NSSL), remotely loaded with steroid decreased serum TGF-β and reduced diaphragm macrophage infiltration. In the long-term, NSSL-MPS demonstrated improved muscle strength and mobility compared to MPS as-is and induced lower tibia and lumbar vertebrae osteoporosis. (Turjeman and Yanay et al 2018)